Calcium gluconate in phosphate buffered saline increases gene delivery with adenovirus type 5.

<h4>Background</h4>Adenoviruses are attractive vectors for gene therapy because of their stability in vivo and the possibility of production at high titers. Despite exciting preclinical data with various approaches, there are only a few examples of clear efficacy in clinical trials. Effe...

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Autores principales: Marko T Ahonen, Iulia Diaconu, Sari Pesonen, Anna Kanerva, Marc Baumann, Suvi T Parviainen, Brad Spiller, Vincenzo Cerullo, Akseli Hemminki
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/fa46758582e148668c18afbb2e95243f
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