Stimulus design for model selection and validation in cell signaling.

Mechanism-based chemical kinetic models are increasingly being used to describe biological signaling. Such models serve to encapsulate current understanding of pathways and to enable insight into complex biological processes. One challenge in model development is that, with limited experimental data...

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Autores principales: Joshua F Apgar, Jared E Toettcher, Drew Endy, Forest M White, Bruce Tidor
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/fab8e059031a4b60914c1ca14447329d
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