Vastly extended drug release from poly(pro-17β-estradiol) materials facilitates in vitro neurotrophism and neuroprotection

Currently there are no therapeutics for long lasting central nervous system injuries, that can address the complex injury cascade that develops over years. Here the authors report biomaterial scaffolds that release 17β-estradiol (E2) at nanomolar concentrations over the course of 1–10 years via slow...

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Auteurs principaux: Anthony R. D’Amato, Devan L. Puhl, Samuel A. T. Ellman, Bailey Balouch, Ryan J. Gilbert, Edmund F. Palermo
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/facc268ea7b44527b13cd95f6a38119e
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