Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation
Abstract Bmp plays an important role in cardiomyocyte differentiation, but the function of Smad4 in Bmp signaling remains elusive. Here, we show that disruption of the Smad4 gene in cardiac progenitors expressing Sfrp5 led to embryonic lethality with hypoplastic heart formation. Although the express...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/facdf754252742c58ba07118dc45ac9e |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|