Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density
Abstract LIN28A overexpression has been identified in malignant brain tumors called embryonal tumors with multilayered rosettes (ETMR) but its specific role during brain development remains largely unknown. Radial glia cells of the ventricular zone (VZ) are proposed as a cell of origin for ETMR. We...
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Main Authors: | , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
BMC
2021
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Subjects: | |
Online Access: | https://doaj.org/article/fafa30e3b2494779a1d5c062439e2ceb |
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