Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density

Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density

Abstract LIN28A overexpression has been identified in malignant brain tumors called embryonal tumors with multilayered rosettes (ETMR) but its specific role during brain development remains largely unknown. Radial glia cells of the ventricular zone (VZ) are proposed as a cell of origin for ETMR. We...

Full description

Saved in:
Bibliographic Details
Main Authors: Maximilian Middelkamp, Lisa Ruck, Christoph Krisp, Piotr Sumisławski, Behnam Mohammadi, Matthias Dottermusch, Valerie Meister, Lukas Küster, Hartmut Schlüter, Sabine Windhorst, Julia E. Neumann
Format: article
Language:EN
Published: BMC 2021
Subjects:
LIN28A
Embryonal tumor
ETMR
Proteomics
Spine density
Microtubule
Neurology. Diseases of the nervous system
RC346-429
Online Access:https://doaj.org/article/fafa30e3b2494779a1d5c062439e2ceb
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/fafa30e3b2494779a1d5c062439e2ceb

Similar Items