Genetic variant rs10251977 (G>A) in EGFR-AS1 modulates the expression of EGFR isoforms A and D

Abstract Tyrosine kinase inhibitor is an effective chemo-therapeutic drug against tumors with deregulated EGFR pathway. Recently, a genetic variant rs10251977 (G>A) in exon 20 of EGFR reported to act as a prognostic marker for HNSCC. Genotyping of this polymorphism in oral cancer patients showed...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Shankar Dhamodharan, Mathew Maria Rose, Sundaram Reddy Chakkarappan, Karuppiah Vijayamuthuramalingam Umadharshini, Ramalingam Arulmurugan, Shanmugam Subbiah, Ituro Inoue, Arasambattu Kannan Munirajan
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/faff5b05fc5f4e8b8985d90024ca286f
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!