Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy.

<h4>Background</h4>Despite guidelines establishing the need to perform comprehensive paediatric drug development programs, pivotal trials in children with epilepsy have been completed mostly in Phase IV as a postapproval replication of adult data. However, it has been shown that the trea...

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Auteurs principaux: Sylvain Rheims, Michel Cucherat, Alexis Arzimanoglou, Philippe Ryvlin
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2008
Sujets:
R
Accès en ligne:https://doaj.org/article/fb2a20c4cb8046bd97338064bec0cecb
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