Cullin3 (CUL3) suppresses proliferation, migration and phenotypic transformation of PDGF-BB-stimulated vascular smooth muscle cells and mitigates inflammatory response by repressing Hedgehog signaling pathway

Vascular smooth muscle cell (VSMC) hyperplasia is closely associated with AS progression. Hence, it is of great significance to elucidate the molecular mechanisms underlying the involvement of VSMCs in AS. SHH antagonist can inhibit the excessive proliferation, migration and phenotypic transformatio...

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Bibliographic Details
Main Authors: Yuluan Xiang, Lihua Li, Shuang Xia, Jinlin Lv, Xiaoling Li
Format: article
Language:EN
Published: Taylor & Francis Group 2021
Subjects:
Online Access:https://doaj.org/article/fb3f4f2911224335aee6c6c51edd5c92
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