The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.
Arrestins are multifunctional signaling adaptors originally discovered as proteins that "arrest" G protein activation by G protein-coupled receptors (GPCRs). Recently GPCR complexes with arrestins have been proposed to activate G protein-independent signaling pathways. In particular, arres...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/fb428791600a42a187f3913576941165 |
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