The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.

The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.

Arrestins are multifunctional signaling adaptors originally discovered as proteins that "arrest" G protein activation by G protein-coupled receptors (GPCRs). Recently GPCR complexes with arrestins have been proposed to activate G protein-independent signaling pathways. In particular, arres...

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Autores principales: Sergio Coffa, Maya Breitman, Susan M Hanson, Kari Callaway, Seunghyi Kook, Kevin N Dalby, Vsevolod V Gurevich
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/fb428791600a42a187f3913576941165
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