Environmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards.

Environmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards.

Oseltamivir (Tamiflu®) is the most widely used drug against influenza infections and is extensively stockpiled worldwide as part of pandemic preparedness plans. However, resistance is a growing problem and in 2008-2009, seasonal human influenza A/H1N1 virus strains in most parts of the world carried...

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Main Authors: Josef D Järhult, Shaman Muradrasoli, John Wahlgren, Hanna Söderström, Goran Orozovic, Gunnar Gunnarsson, Caroline Bröjer, Neus Latorre-Margalef, Jerker Fick, Roman Grabic, Johan Lennerstrand, Jonas Waldenström, Ake Lundkvist, Björn Olsen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/fb449c3e127349b8b9eb8188b851bc0e
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