Mistranslation can enhance fitness through purging of deleterious mutations

Mistranslation results in amino acid changes in proteins known as phenotypic mutations and these occur at a much higher rate than DNA mutations. Here, the authors show that mistranslation can increase the response to directional selection by exacerbating the fitness effects of deleterious DNA mutati...

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Autores principales: Sinisa Bratulic, Macarena Toll-Riera, Andreas Wagner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/fb502bf724b9452c9364e777945360ab
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