HIV acquisition is associated with increased antimicrobial peptides and reduced HIV neutralizing IgA in the foreskin prepuce of uncircumcised men.

HIV acquisition is associated with increased antimicrobial peptides and reduced HIV neutralizing IgA in the foreskin prepuce of uncircumcised men.

<h4>Background</h4>The foreskin is the site of most HIV acquisition in uncircumcised heterosexual men. Although HIV-exposed, seronegative (HESN) uncircumcised men demonstrate HIV-neutralizing IgA and increased antimicrobial peptides (AMPs) in the foreskin prepuce, no prospective studies...

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Bibliographic Details
Main Authors: Taha Hirbod, Xiangrong Kong, Godgrey Kigozi, Anthony Ndyanabo, David Serwadda, Jessica L Prodger, Aaron A Tobian, Fred Nalugoda, Maria J Wawer, Kamnoosh Shahabi, Olga L Rojas, Jennifer L Gommerman, Kristina Broliden, Rupert Kaul, Ronald H Gray
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/fb6f8a3c7bfe484f8348c03156744fad
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https://doaj.org/article/fb6f8a3c7bfe484f8348c03156744fad

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