HIV acquisition is associated with increased antimicrobial peptides and reduced HIV neutralizing IgA in the foreskin prepuce of uncircumcised men.
<h4>Background</h4>The foreskin is the site of most HIV acquisition in uncircumcised heterosexual men. Although HIV-exposed, seronegative (HESN) uncircumcised men demonstrate HIV-neutralizing IgA and increased antimicrobial peptides (AMPs) in the foreskin prepuce, no prospective studies...
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Main Authors: | Taha Hirbod, Xiangrong Kong, Godgrey Kigozi, Anthony Ndyanabo, David Serwadda, Jessica L Prodger, Aaron A Tobian, Fred Nalugoda, Maria J Wawer, Kamnoosh Shahabi, Olga L Rojas, Jennifer L Gommerman, Kristina Broliden, Rupert Kaul, Ronald H Gray |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/fb6f8a3c7bfe484f8348c03156744fad |
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