PASTA kinase-dependent control of peptidoglycan synthesis via ReoM is required for cell wall stress responses, cytosolic survival, and virulence in Listeria monocytogenes.

Pathogenic bacteria rely on protein phosphorylation to adapt quickly to stress, including that imposed by the host during infection. Penicillin-binding protein and serine/threonine-associated (PASTA) kinases are signal transduction systems that sense cell wall integrity and modulate multiple facets...

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Autores principales: Jessica L Kelliher, Caroline M Grunenwald, Rhiannon R Abrahams, McKenzie E Daanen, Cassandra I Lew, Warren E Rose, John-Demian Sauer
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/fb8a1d14f47a4375b9c8dcb89d97cf49
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