Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection

Chromatin dynamics is thought to play an important role in the maintenance of telomeres, yet how has remained poorly understood. Here the authors locally enrich heterochromatin protein 1α (HP1α) at human telomeres to provide insights into the crosstalk between epigenetic regulations and structural d...

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Auteurs principaux: Tracy T. Chow, Xiaoyu Shi, Jen-Hsuan Wei, Juan Guan, Guido Stadler, Bo Huang, Elizabeth H. Blackburn
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/fba23e2f45694006b4935b2e453fa373
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