Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection

Chromatin dynamics is thought to play an important role in the maintenance of telomeres, yet how has remained poorly understood. Here the authors locally enrich heterochromatin protein 1α (HP1α) at human telomeres to provide insights into the crosstalk between epigenetic regulations and structural d...

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Autores principales:	Tracy T. Chow, Xiaoyu Shi, Jen-Hsuan Wei, Juan Guan, Guido Stadler, Bo Huang, Elizabeth H. Blackburn
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fba23e2f45694006b4935b2e453fa373
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spelling	oai:doaj.org-article:fba23e2f45694006b4935b2e453fa3732021-12-02T14:39:26ZLocal enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection10.1038/s41467-018-05840-y2041-1723https://doaj.org/article/fba23e2f45694006b4935b2e453fa3732018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05840-yhttps://doaj.org/toc/2041-1723Chromatin dynamics is thought to play an important role in the maintenance of telomeres, yet how has remained poorly understood. Here the authors locally enrich heterochromatin protein 1α (HP1α) at human telomeres to provide insights into the crosstalk between epigenetic regulations and structural dynamics at the telomeres.Tracy T. ChowXiaoyu ShiJen-Hsuan WeiJuan GuanGuido StadlerBo HuangElizabeth H. BlackburnNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tracy T. Chow Xiaoyu Shi Jen-Hsuan Wei Juan Guan Guido Stadler Bo Huang Elizabeth H. Blackburn Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
description	Chromatin dynamics is thought to play an important role in the maintenance of telomeres, yet how has remained poorly understood. Here the authors locally enrich heterochromatin protein 1α (HP1α) at human telomeres to provide insights into the crosstalk between epigenetic regulations and structural dynamics at the telomeres.
format	article
author	Tracy T. Chow Xiaoyu Shi Jen-Hsuan Wei Juan Guan Guido Stadler Bo Huang Elizabeth H. Blackburn
author_facet	Tracy T. Chow Xiaoyu Shi Jen-Hsuan Wei Juan Guan Guido Stadler Bo Huang Elizabeth H. Blackburn
author_sort	Tracy T. Chow
title	Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
title_short	Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
title_full	Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
title_fullStr	Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
title_full_unstemmed	Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
title_sort	local enrichment of hp1alpha at telomeres alters their structure and regulation of telomere protection
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/fba23e2f45694006b4935b2e453fa373
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Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection

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