HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles

Bauzá-Martinez et al. analyzed the HLA-I peptide ligandome in extracellular vesicles (EVs) from an EBV-immortalized B cell line, JY, and compare HLA-I-binding peptides recovered from EVs to those recovered from whole-cells. The authors report an enrichment for HLA-B-binding peptides and for post-tra...

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Bibliographic Details
Main Authors: Julia Bauzá-Martinez, Albert J. R. Heck, Wei Wu
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Online Access:https://doaj.org/article/fbaffa91552645889971ca88dba9c128
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