HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles

Bauzá-Martinez et al. analyzed the HLA-I peptide ligandome in extracellular vesicles (EVs) from an EBV-immortalized B cell line, JY, and compare HLA-I-binding peptides recovered from EVs to those recovered from whole-cells. The authors report an enrichment for HLA-B-binding peptides and for post-tra...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Julia Bauzá-Martinez, Albert J. R. Heck, Wei Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/fbaffa91552645889971ca88dba9c128
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fbaffa91552645889971ca88dba9c128
record_format	dspace
spelling	oai:doaj.org-article:fbaffa91552645889971ca88dba9c1282021-12-02T16:32:08ZHLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles10.1038/s42003-021-02364-y2399-3642https://doaj.org/article/fbaffa91552645889971ca88dba9c1282021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02364-yhttps://doaj.org/toc/2399-3642Bauzá-Martinez et al. analyzed the HLA-I peptide ligandome in extracellular vesicles (EVs) from an EBV-immortalized B cell line, JY, and compare HLA-I-binding peptides recovered from EVs to those recovered from whole-cells. The authors report an enrichment for HLA-B-binding peptides and for post-translationally modified cysteinylated peptides in EVs as compared to whole-cells.Julia Bauzá-MartinezAlbert J. R. HeckWei WuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Julia Bauzá-Martinez Albert J. R. Heck Wei Wu HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
description	Bauzá-Martinez et al. analyzed the HLA-I peptide ligandome in extracellular vesicles (EVs) from an EBV-immortalized B cell line, JY, and compare HLA-I-binding peptides recovered from EVs to those recovered from whole-cells. The authors report an enrichment for HLA-B-binding peptides and for post-translationally modified cysteinylated peptides in EVs as compared to whole-cells.
format	article
author	Julia Bauzá-Martinez Albert J. R. Heck Wei Wu
author_facet	Julia Bauzá-Martinez Albert J. R. Heck Wei Wu
author_sort	Julia Bauzá-Martinez
title	HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
title_short	HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
title_full	HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
title_fullStr	HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
title_full_unstemmed	HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
title_sort	hla-b and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fbaffa91552645889971ca88dba9c128
work_keys_str_mv	AT juliabauzamartinez hlabandcysteinylatedligandsdistinguishtheantigenpresentationlandscapeofextracellularvesicles AT albertjrheck hlabandcysteinylatedligandsdistinguishtheantigenpresentationlandscapeofextracellularvesicles AT weiwu hlabandcysteinylatedligandsdistinguishtheantigenpresentationlandscapeofextracellularvesicles
_version_	1718383849478553600

HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles

Ejemplares similares