USP13 negatively regulates antiviral responses by deubiquitinating STING
The cGAS-STING pathway is a DNA sensing mechanism that enables response to viral infection by inducing type 1 interferon expression. Here the authors show a mechanism by which the deubiquitinating enzyme USP13 prevents STING from enabling response to virus.
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/fbc5fe9e9ef2487986b6042fd5305778 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|