A single disulfide bond disruption in the β3 integrin subunit promotes thiol/disulfide exchange, a molecular dynamics study.

The integrins are a family of membrane receptors that attach a cell to its surrounding and play a crucial function in cell signaling. The combination of internal and external stimuli alters a folded non-active state of these proteins to an extended active configuration. The β3 subunit of the platele...

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Autores principales: Lihie Levin, Ehud Zelzion, Esther Nachliel, Menachem Gutman, Yossi Tsfadia, Yulia Einav
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/fc01216f59af43409f8379f93dadfa70
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