A single disulfide bond disruption in the β3 integrin subunit promotes thiol/disulfide exchange, a molecular dynamics study.
The integrins are a family of membrane receptors that attach a cell to its surrounding and play a crucial function in cell signaling. The combination of internal and external stimuli alters a folded non-active state of these proteins to an extended active configuration. The β3 subunit of the platele...
Guardado en:
Autores principales: | Lihie Levin, Ehud Zelzion, Esther Nachliel, Menachem Gutman, Yossi Tsfadia, Yulia Einav |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/fc01216f59af43409f8379f93dadfa70 |
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