Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV

Abstract Hepatitis B Virus (HBV) constitutes a major threat to global public health. Current understanding of HBV-host interaction is yet limited. Here, ribosome profiling, quantitative mass spectrometry and RNA-sequencing were conducted on a recently established HBV replication system, through whic...

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Autores principales: Shilin Yuan, Guanghong Liao, Menghuan Zhang, Yuanfei Zhu, Weidi Xiao, Kun Wang, Chuanyin Li, Caiwei Jia, Na Sun, Axel Walch, Daming Gao, Ping Xu, Qiang Deng, Jian Zhang, He Wang, Ronggui Hu
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/fc77a95c75fc478a9f29455679530875
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