Shrinking the metabolic solution space using experimental datasets.

Constraint-based models of metabolism have been used in a variety of studies on drug discovery, metabolic engineering, evolution, and multi-species interactions. These genome-scale models can be generated for any sequenced organism since their main parameters (i.e., reaction stoichiometry) are highl...

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Bibliographic Details
Main Author: Jennifer L Reed
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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Online Access:https://doaj.org/article/fcb5c40563fd4cb89a9e9eaeb26f656f
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