Antibiotic collateral sensitivity is contingent on the repeatability of evolution

The evolution of resistance to an antibiotic can render bacteria more susceptible, or more resistant, to a second antibiotic. Here, Nichol et al. provide evidence that the final outcome can be fairly stochastic and depends on the shape of the evolutionary fitness landscape.

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Detalles Bibliográficos
Autores principales: Daniel Nichol, Joseph Rutter, Christopher Bryant, Andrea M. Hujer, Sai Lek, Mark D. Adams, Peter Jeavons, Alexander R. A. Anderson, Robert A. Bonomo, Jacob G. Scott
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fcd27466c5b448a4a8dd0543dc7be5c4
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