Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants

Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants

Adeno-associated virus is the basis of many gene therapies and gene transfer vectors. Here the authors report a pipeline to enable side-by-side comparison of pre-selected capsids in a high throughput manner.

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Autores principales: Jonas Weinmann, Sabrina Weis, Josefine Sippel, Warut Tulalamba, Anca Remes, Jihad El Andari, Anne-Kathrin Herrmann, Quang H. Pham, Christopher Borowski, Susanne Hille, Tanja Schönberger, Norbert Frey, Martin Lenter, Thierry VandenDriessche, Oliver J. Müller, Marinee K. Chuah, Thorsten Lamla, Dirk Grimm
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/fcda7a44d2044540880d0f383706efd9
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https://doaj.org/article/fcda7a44d2044540880d0f383706efd9

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