Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants

Adeno-associated virus is the basis of many gene therapies and gene transfer vectors. Here the authors report a pipeline to enable side-by-side comparison of pre-selected capsids in a high throughput manner.

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Autores principales:	Jonas Weinmann, Sabrina Weis, Josefine Sippel, Warut Tulalamba, Anca Remes, Jihad El Andari, Anne-Kathrin Herrmann, Quang H. Pham, Christopher Borowski, Susanne Hille, Tanja Schönberger, Norbert Frey, Martin Lenter, Thierry VandenDriessche, Oliver J. Müller, Marinee K. Chuah, Thorsten Lamla, Dirk Grimm
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fcda7a44d2044540880d0f383706efd9
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spelling	oai:doaj.org-article:fcda7a44d2044540880d0f383706efd92021-12-02T15:39:23ZIdentification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants10.1038/s41467-020-19230-w2041-1723https://doaj.org/article/fcda7a44d2044540880d0f383706efd92020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19230-whttps://doaj.org/toc/2041-1723Adeno-associated virus is the basis of many gene therapies and gene transfer vectors. Here the authors report a pipeline to enable side-by-side comparison of pre-selected capsids in a high throughput manner.Jonas WeinmannSabrina WeisJosefine SippelWarut TulalambaAnca RemesJihad El AndariAnne-Kathrin HerrmannQuang H. PhamChristopher BorowskiSusanne HilleTanja SchönbergerNorbert FreyMartin LenterThierry VandenDriesscheOliver J. MüllerMarinee K. ChuahThorsten LamlaDirk GrimmNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jonas Weinmann Sabrina Weis Josefine Sippel Warut Tulalamba Anca Remes Jihad El Andari Anne-Kathrin Herrmann Quang H. Pham Christopher Borowski Susanne Hille Tanja Schönberger Norbert Frey Martin Lenter Thierry VandenDriessche Oliver J. Müller Marinee K. Chuah Thorsten Lamla Dirk Grimm Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
description	Adeno-associated virus is the basis of many gene therapies and gene transfer vectors. Here the authors report a pipeline to enable side-by-side comparison of pre-selected capsids in a high throughput manner.
format	article
author	Jonas Weinmann Sabrina Weis Josefine Sippel Warut Tulalamba Anca Remes Jihad El Andari Anne-Kathrin Herrmann Quang H. Pham Christopher Borowski Susanne Hille Tanja Schönberger Norbert Frey Martin Lenter Thierry VandenDriessche Oliver J. Müller Marinee K. Chuah Thorsten Lamla Dirk Grimm
author_facet	Jonas Weinmann Sabrina Weis Josefine Sippel Warut Tulalamba Anca Remes Jihad El Andari Anne-Kathrin Herrmann Quang H. Pham Christopher Borowski Susanne Hille Tanja Schönberger Norbert Frey Martin Lenter Thierry VandenDriessche Oliver J. Müller Marinee K. Chuah Thorsten Lamla Dirk Grimm
author_sort	Jonas Weinmann
title	Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
title_short	Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
title_full	Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
title_fullStr	Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
title_full_unstemmed	Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
title_sort	identification of a myotropic aav by massively parallel in vivo evaluation of barcoded capsid variants
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/fcda7a44d2044540880d0f383706efd9
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Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants

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