Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

Abstract The brain-expressed ubiquilins, UBQLNs 1, 2 and 4, are highly homologous proteins that participate in multiple aspects of protein homeostasis and are implicated in neurodegenerative diseases. Studies have established that UBQLN2 forms liquid-like condensates and accumulates in pathogenic ag...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Julia E. Gerson, Hunter Linton, Jiazheng Xing, Alexandra B. Sutter, Fayth S. Kakos, Jaimie Ryou, Nyjerus Liggans, Lisa M. Sharkey, Nathaniel Safren, Henry L. Paulson, Magdalena I. Ivanova
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/fcee382d1ef546399d85f2b4630abc8a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!