Structure based prediction of a novel GPR120 antagonist based on pharmacophore screening and molecular dynamics simulations

The G-protein coupled receptor, GPR120, has ubiquitous expression and multifaceted roles in modulating metabolic and anti-inflammatory processes. Recent implications of its role in cancer progression have presented GPR120 as an attractive oncogenic drug target. GPR120 gene knockdown in breast cancer...

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Détails bibliographiques
Auteurs principaux: Ajay Pal, James F. Curtin, Gemma K. Kinsella
Format: article
Langue:EN
Publié: Elsevier 2021
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Accès en ligne:https://doaj.org/article/fcf19c2399204e4fa659764299d2f8fb
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