Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics

Abstract Short or small interfering RNAs (siRNAs) and microRNA (miRNAs) are molecules similar in size and function able to inhibit gene expression based on their complementarity with mRNA sequences, inducing the degradation of the transcript or the inhibition of their translation. siRNAs bind specif...

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Autores principales: Rossana Cuciniello, Stefania Filosa, Stefania Crispi
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/fcf3b7a0335c47fbbc21459771cd2164
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