Symmetrically dimethylated histone H3R2 promotes global transcription during minor zygotic genome activation in mouse pronuclei
Abstract Paternal genome reprogramming, such as protamine–histone exchange and global DNA demethylation, is crucial for the development of fertilised embryos. Previously, our study showed that one of histone arginine methylation, asymmetrically dimethylated histone H3R17 (H3R17me2a), is necessary fo...
Saved in:
Main Authors: | Kohtaro Morita, Yuki Hatanaka, Shunya Ihashi, Masahide Asano, Kei Miyamoto, Kazuya Matsumoto |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/fcf3c10f47fa40f084b91b050f1310a6 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Histone variant H2A.Z regulates zygotic genome activation
by: Dafne Ibarra-Morales, et al.
Published: (2021) -
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
by: Qing-Jun Zhang, et al.
Published: (2018) -
Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases
by: Kei Fukuda, et al.
Published: (2021) -
Totipotency of mouse zygotes extends to single blastomeres of embryos at the four-cell stage
by: Marino Maemura, et al.
Published: (2021) -
Two mechanisms drive pronuclear migration in mouse zygotes
by: Kathleen Scheffler, et al.
Published: (2021)