Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug

Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug

Abstract Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have restricted its chemotherapeutic potential. To overcome these restrictions, CPT was encapsulated in CEF (cyclodextrin-EDTA-FE3O4), a co...

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Auteurs principaux: Poorani Krishnan, Mariappan Rajan, Sharmilah Kumari, S. Sakinah, Sivan Padma Priya, Fatin Amira, Lawal Danjuma, Mok Pooi Ling, Sharida Fakurazi, Palanisamy Arulselvan, Akon Higuchi, Ramitha Arumugam, Abdullah A. Alarfaj, Murugan A. Munusamy, Rukman Awang Hamat, Giovanni Benelli, Kadarkarai Murugan, S. Suresh Kumar
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/fd17cfce15764f71a8324eb089ef8a94
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https://doaj.org/article/fd17cfce15764f71a8324eb089ef8a94

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