ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection

ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection

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Despite antibody-dependent cellular cytotoxicity (ADCC) responses being implicated in protection from HIV-1 infection, there is limited evidence that they control virus replication. The high mutability of HIV-1 enables the virus to rapidly adapt, and thus evidence of viral escape is a very sensitive...

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Bibliographic Details
Main Authors: Dieter Mielke, Gama Bandawe, Jie Zheng, Jennifer Jones, Melissa-Rose Abrahams, Valerie Bekker, Christina Ochsenbauer, Nigel Garrett, Salim Abdool Karim, Penny L. Moore, Lynn Morris, David Montefiori, Colin Anthony, Guido Ferrari, Carolyn Williamson
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/fd1a9e56d1df41cf85ae7238ccf3f401
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https://doaj.org/article/fd1a9e56d1df41cf85ae7238ccf3f401

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