Sirtuin 7 Regulates Nitric Oxide Production and Apoptosis to Promote Mycobacterial Clearance in Macrophages

The host immune system plays a pivotal role in the containment of Mycobacterium tuberculosis (Mtb) infection, and host-directed therapy (HDT) is emerging as an effective strategy to treat tuberculosis (TB), especially drug-resistant TB. Previous studies revealed that expression of sirtuin 7 (SIRT7),...

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Auteurs principaux: Su Zhang, Yaya Liu, Xuefeng Zhou, Min Ou, Guohui Xiao, Fang Li, Zhongyuan Wang, Zhaoqin Wang, Lei Liu, Guoliang Zhang
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/fd249f0fbb504cbeb8b815d439d1b8a4
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