Genomic landscape of platinum resistant and sensitive testicular cancers

Genomic landscape of platinum resistant and sensitive testicular cancers

Most testicular germ-cell tumours are exquisitely sensitive to platinum-based chemotherapies, but little is known about why 10% are resistant. Here, the authors explore the potential underlying mechanisms by probing the genomic landscape of platinum-resistant disease.

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Auteurs principaux: Chey Loveday, Kevin Litchfield, Paula Z. Proszek, Alex J. Cornish, Flavia Santo, Max Levy, Geoff Macintyre, Amy Holryod, Peter Broderick, Darshna Dudakia, Barbara Benton, Maise Al Bakir, Crispin Hiley, Emily Grist, Charles Swanton, Robert Huddart, Tom Powles, Simon Chowdhury, Janet Shipley, Simon O’Connor, James D. Brenton, Alison Reid, David Gonzalez de Castro, Richard S. Houlston, Clare Turnbull
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/fd830b167ba2414b9bc17a0f92cc02a5
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Internet

https://doaj.org/article/fd830b167ba2414b9bc17a0f92cc02a5

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