Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine
Abstract Background Cancer is a somatic evolutionary disease and adenocarcinomas of the stomach and gastroesophageal junction (GC) may serve as a two-dimensional model of cancer expansion, in which tumor subclones are not evenly mixed during tumor progression but rather spatially separated and diver...
Saved in:
| Main Authors: | Christoph Röcken, Anu Amallraja, Christine Halske, Luka Opasic, Arne Traulsen, Hans-Michael Behrens, Sandra Krüger, Anne Liu, Jochen Haag, Jan-Hendrik Egberts, Philip Rosenstiel, Tobias Meißner |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
BMC
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/fd8df01746ac4a9f8e7885c8e7424eff |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tumor Heterogeneity and Consequences for Bladder Cancer Treatment
by: Etienne Lavallee, et al.
Published: (2021) -
A Portrait of Intratumoral Genomic and Transcriptomic Heterogeneity at Single-Cell Level in Colorectal Cancer
by: Andrea Angius, et al.
Published: (2021) -
Intratumor Heterogeneity in Hepatocellular Carcinoma: Challenges and Opportunities
by: Sharanya Maanasi Kalasekar, et al.
Published: (2021) -
Intratumoral Heterogeneity and Immune Response Indicators to Predict Overall Survival in a Retrospective Study of HER2-Borderline (IHC 2+) Breast Cancer Patients
by: Gedmante Radziuviene, et al.
Published: (2021) -
Neoadjuvant/Perioperative Treatment Affects Spatial Distribution and Densities of Tumor Associated Neutrophils and CD8+ Lymphocytes in Gastric Cancer
by: Anne Hoffmann, et al.
Published: (2021)