Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing

There is a need to understand how mammary epithelial cells respond to changes at various developmental stages. Here, the authors use single-cell RNA sequencing of mammary epithelial cells at different adult developmental stages, identifying different cell types and charting their developmental traje...

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Autores principales: Karsten Bach, Sara Pensa, Marta Grzelak, James Hadfield, David J. Adams, John C. Marioni, Walid T. Khaled
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/fd8ecac2cc4d4bdd8cce30ec3209934c
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spelling oai:doaj.org-article:fd8ecac2cc4d4bdd8cce30ec3209934c2021-12-02T14:42:07ZDifferentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing10.1038/s41467-017-02001-52041-1723https://doaj.org/article/fd8ecac2cc4d4bdd8cce30ec3209934c2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02001-5https://doaj.org/toc/2041-1723There is a need to understand how mammary epithelial cells respond to changes at various developmental stages. Here, the authors use single-cell RNA sequencing of mammary epithelial cells at different adult developmental stages, identifying different cell types and charting their developmental trajectory.Karsten BachSara PensaMarta GrzelakJames HadfieldDavid J. AdamsJohn C. MarioniWalid T. KhaledNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Karsten Bach
Sara Pensa
Marta Grzelak
James Hadfield
David J. Adams
John C. Marioni
Walid T. Khaled
Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
description There is a need to understand how mammary epithelial cells respond to changes at various developmental stages. Here, the authors use single-cell RNA sequencing of mammary epithelial cells at different adult developmental stages, identifying different cell types and charting their developmental trajectory.
format article
author Karsten Bach
Sara Pensa
Marta Grzelak
James Hadfield
David J. Adams
John C. Marioni
Walid T. Khaled
author_facet Karsten Bach
Sara Pensa
Marta Grzelak
James Hadfield
David J. Adams
John C. Marioni
Walid T. Khaled
author_sort Karsten Bach
title Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
title_short Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
title_full Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
title_fullStr Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
title_full_unstemmed Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
title_sort differentiation dynamics of mammary epithelial cells revealed by single-cell rna sequencing
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/fd8ecac2cc4d4bdd8cce30ec3209934c
work_keys_str_mv AT karstenbach differentiationdynamicsofmammaryepithelialcellsrevealedbysinglecellrnasequencing
AT sarapensa differentiationdynamicsofmammaryepithelialcellsrevealedbysinglecellrnasequencing
AT martagrzelak differentiationdynamicsofmammaryepithelialcellsrevealedbysinglecellrnasequencing
AT jameshadfield differentiationdynamicsofmammaryepithelialcellsrevealedbysinglecellrnasequencing
AT davidjadams differentiationdynamicsofmammaryepithelialcellsrevealedbysinglecellrnasequencing
AT johncmarioni differentiationdynamicsofmammaryepithelialcellsrevealedbysinglecellrnasequencing
AT walidtkhaled differentiationdynamicsofmammaryepithelialcellsrevealedbysinglecellrnasequencing
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