Synthesis of Polypeptides with High-Fidelity Terminal Functionalities under NCA Monomer-Starved Conditions
Controlled polypeptide synthesis via α-amino acid N-carboxylic anhydride (NCA) polymerization using conventional primary amine initiators encounters two major obstacles: (i) normal amine mechanism (NAM) and activated monomer mechanism (AMM) coexist due to amine basicity and nucleophilicity and (ii)...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
American Association for the Advancement of Science
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/fdd4b9990a01414e8b470d074ea53dfa |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|