Tissue plasminogen activator is a ligand of cation-independent mannose 6-phosphate receptor and consists of glycoforms that contain mannose 6-phosphate

Abstract Plasmin is the key enzyme in fibrinolysis. Upon interaction with plasminogen activators, the zymogen plasminogen is converted to active plasmin. Some studies indicate plasminogen activation is regulated by cation-independent mannose 6-phosphate receptor (CI-MPR), a protein that facilitates...

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Bibliographic Details
Main Authors: James J. Miller, Richard N. Bohnsack, Linda J. Olson, Mayumi Ishihara, Kazuhiro Aoki, Michael Tiemeyer, Nancy M. Dahms
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/fde1c5baefca4b609a982fe1a797a5ad
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