Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization

The polarisome is a dynamic protein complex that nucleates F-actin for polarized yeast growth, but its regulation is unclear. Here, the authors report that the polarisome protein Aip5 undergoes Spa2-mediated phase separation in physiological and stress conditions, potentially for regulating actin as...

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Autores principales: Ying Xie, Jialin Sun, Xiao Han, Alma Turšić-Wunder, Joel D. W. Toh, Wanjin Hong, Yong-Gui Gao, Yansong Miao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fde854059e324f8b8624241806154b39
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