Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization

The polarisome is a dynamic protein complex that nucleates F-actin for polarized yeast growth, but its regulation is unclear. Here, the authors report that the polarisome protein Aip5 undergoes Spa2-mediated phase separation in physiological and stress conditions, potentially for regulating actin as...

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Autores principales:	Ying Xie, Jialin Sun, Xiao Han, Alma Turšić-Wunder, Joel D. W. Toh, Wanjin Hong, Yong-Gui Gao, Yansong Miao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fde854059e324f8b8624241806154b39
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spelling	oai:doaj.org-article:fde854059e324f8b8624241806154b392021-12-02T14:35:37ZPolarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization10.1038/s41467-019-13125-12041-1723https://doaj.org/article/fde854059e324f8b8624241806154b392019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13125-1https://doaj.org/toc/2041-1723The polarisome is a dynamic protein complex that nucleates F-actin for polarized yeast growth, but its regulation is unclear. Here, the authors report that the polarisome protein Aip5 undergoes Spa2-mediated phase separation in physiological and stress conditions, potentially for regulating actin assembly.Ying XieJialin SunXiao HanAlma Turšić-WunderJoel D. W. TohWanjin HongYong-Gui GaoYansong MiaoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ying Xie Jialin Sun Xiao Han Alma Turšić-Wunder Joel D. W. Toh Wanjin Hong Yong-Gui Gao Yansong Miao Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization
description	The polarisome is a dynamic protein complex that nucleates F-actin for polarized yeast growth, but its regulation is unclear. Here, the authors report that the polarisome protein Aip5 undergoes Spa2-mediated phase separation in physiological and stress conditions, potentially for regulating actin assembly.
format	article
author	Ying Xie Jialin Sun Xiao Han Alma Turšić-Wunder Joel D. W. Toh Wanjin Hong Yong-Gui Gao Yansong Miao
author_facet	Ying Xie Jialin Sun Xiao Han Alma Turšić-Wunder Joel D. W. Toh Wanjin Hong Yong-Gui Gao Yansong Miao
author_sort	Ying Xie
title	Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization
title_short	Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization
title_full	Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization
title_fullStr	Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization
title_full_unstemmed	Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization
title_sort	polarisome scaffolder spa2-mediated macromolecular condensation of aip5 for actin polymerization
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/fde854059e324f8b8624241806154b39
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_version_	1718391110733135872

Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization

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