Functional organization of protein determinants of meiotic DNA break hotspots

Abstract During Schizosaccharomyces pombe meiotic prophase, homologous chromosomes are co-aligned by linear elements (LinEs) analogous to the axial elements of the synaptonemal complex (SC) in other organisms. LinE proteins also promote the formation of meiotic DNA double-strand breaks (DSBs), the p...

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Auteurs principaux: Lijuan Ma, Kyle R. Fowler, Cristina Martín-Castellanos, Gerald R. Smith
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/fdf1defa6ef34b55a79dabb06be7e905
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