A novel mechanism linking memory stem cells with innate immunity in protection against HIV-1 infection

A novel mechanism linking memory stem cells with innate immunity in protection against HIV-1 infection

Abstract HIV infection affects 37 million people and about 1.7 million are infected annually. Among the phase III clinical trials only the RV144 vaccine trial elicited significant protection against HIV-1 acquisition, but the efficacy and immune memory were inadequate. To boost these vaccine functio...

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Main Authors: Yufei Wang, Trevor Whittall, Stuart Neil, Gary Britton, Mukesh Mistry, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Jaranit Kaewkungwal, Sorachai Nitayaphan, Xuesong Yu, Alicia Sato, Robert J. O’Connell, Nelson L. Michael, Merlin L. Robb, Jerome H. Kim, Thomas Lehner
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/fe03733a163a4761833618d8fb3d76d0
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