Dietary improvement of the iron statute of the rats with experimental anemia
Introduction. One of the major problems characterizing the nutritional status is the iron deficiency, which leads to decreased immunity, increased incidence of infectious diseases and anemia. Obviously, only well-thought-out corrections can solve these disorders. Material and methods In order to k...
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Asociatia de Biosiguranta si Biosecuritate
2021
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oai:doaj.org-article:fe07366ad0354653b1403985d611ce862021-12-02T14:22:43ZDietary improvement of the iron statute of the rats with experimental anemia10.38045/ohrm.2021.1.022887-34582587-3466https://doaj.org/article/fe07366ad0354653b1403985d611ce862021-01-01T00:00:00Zhttps://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/89/49https://doaj.org/toc/2887-3458https://doaj.org/toc/2587-3466Introduction. One of the major problems characterizing the nutritional status is the iron deficiency, which leads to decreased immunity, increased incidence of infectious diseases and anemia. Obviously, only well-thought-out corrections can solve these disorders. Material and methods In order to know the influence of the method of manufacture for iron-fortified products on the iron level, a series of in vivo research was carried out, on a batch of 21 white rats, Wistar line, which were induced experimental drug anemia (EDA). The blood analysis was performed in three stages: initially, after the induction of EDA and after the completion of the experiment. Results. Investigations showed out that during sufficient iron intake rehabilitation of the body iron reserve depends considerably on the presence of antinutritive factors. In order to decrease the influence of these factors, the production method used for fortified products with mineral origin micronutrients (iron) could be based on the use of the lactic-acid fermentation procedures using wheat bran. Conclusions. The research carried out on laboratory animals with induced experimental anemia showed that, in the case of the group fed with bread manufactured by the acid-lactic fermentation method, the concentration of serum, iron was completely restored during the experiment, and in the rats fed with fortified bread prepared by the traditional method, the serum iron concentration was only partially restored, 40-45%.Rodica STURZAValentin GUDUMACOlga DESEATNICOVAAliona GHENDOV-MOSANUAsociatia de Biosiguranta si Biosecuritatearticleiron anemiaratsvivo researchfortified breadlactic acid fermentationperipheral blood parametersserum ironMedicineRScienceQENFRRORUOne Health & Risk Management, Vol 2, Iss 1, Pp 13-21 (2021) |
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iron anemia rats vivo research fortified bread lactic acid fermentation peripheral blood parameters serum iron Medicine R Science Q |
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iron anemia rats vivo research fortified bread lactic acid fermentation peripheral blood parameters serum iron Medicine R Science Q Rodica STURZA Valentin GUDUMAC Olga DESEATNICOVA Aliona GHENDOV-MOSANU Dietary improvement of the iron statute of the rats with experimental anemia |
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Introduction. One of the major problems characterizing the nutritional status is the iron deficiency, which leads to decreased immunity, increased incidence of infectious diseases and anemia. Obviously, only well-thought-out corrections can solve these disorders.
Material and methods In order to know the influence of the method of manufacture for iron-fortified products on the iron level, a series of in vivo research was carried out, on a batch of 21 white rats, Wistar line, which were induced experimental drug anemia (EDA). The blood analysis was performed in three stages: initially, after the induction of EDA and after the completion of the experiment.
Results. Investigations showed out that during sufficient iron intake rehabilitation of the body iron reserve depends considerably on the presence of antinutritive factors. In order to decrease the influence of these factors, the production method used for fortified products with mineral origin micronutrients (iron) could be based on the use of the lactic-acid fermentation procedures using wheat bran.
Conclusions. The research carried out on laboratory animals with induced experimental anemia showed that, in the case of the group fed with bread manufactured by the acid-lactic fermentation method, the concentration of serum, iron was completely restored during the experiment, and in the rats fed with fortified bread prepared by the traditional method, the serum iron concentration was only partially restored, 40-45%. |
format |
article |
author |
Rodica STURZA Valentin GUDUMAC Olga DESEATNICOVA Aliona GHENDOV-MOSANU |
author_facet |
Rodica STURZA Valentin GUDUMAC Olga DESEATNICOVA Aliona GHENDOV-MOSANU |
author_sort |
Rodica STURZA |
title |
Dietary improvement of the iron statute of the rats with experimental anemia |
title_short |
Dietary improvement of the iron statute of the rats with experimental anemia |
title_full |
Dietary improvement of the iron statute of the rats with experimental anemia |
title_fullStr |
Dietary improvement of the iron statute of the rats with experimental anemia |
title_full_unstemmed |
Dietary improvement of the iron statute of the rats with experimental anemia |
title_sort |
dietary improvement of the iron statute of the rats with experimental anemia |
publisher |
Asociatia de Biosiguranta si Biosecuritate |
publishDate |
2021 |
url |
https://doaj.org/article/fe07366ad0354653b1403985d611ce86 |
work_keys_str_mv |
AT rodicasturza dietaryimprovementoftheironstatuteoftheratswithexperimentalanemia AT valentingudumac dietaryimprovementoftheironstatuteoftheratswithexperimentalanemia AT olgadeseatnicova dietaryimprovementoftheironstatuteoftheratswithexperimentalanemia AT alionaghendovmosanu dietaryimprovementoftheironstatuteoftheratswithexperimentalanemia |
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