Homocystamide Conjugates of Human Serum Albumin as a Platform to Prepare Bimodal Multidrug Delivery Systems for Boron Neutron Capture Therapy

Homocystamide Conjugates of Human Serum Albumin as a Platform to Prepare Bimodal Multidrug Delivery Systems for Boron Neutron Capture Therapy

Boron neutron capture therapy is a unique form of adjuvant cancer therapy for various malignancies including malignant gliomas. The conjugation of boron compounds and human serum albumin (HSA)—a carrier protein with a long plasma half-life—is expected to extend systemic circulation of the boron comp...

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Auteurs principaux: Tatyana Popova, Maya A. Dymova, Ludmila S. Koroleva, Olga D. Zakharova, Vladimir A. Lisitskiy, Valeria I. Raskolupova, Tatiana Sycheva, Sergei Taskaev, Vladimir N. Silnikov, Tatyana S. Godovikova
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
boron neutron capture therapy
boron delivery agents
thenoyltrifluoroacetone
boronated albumin theranostic
conjugate
in vitro efficacy evaluation
Organic chemistry
QD241-441
Accès en ligne:https://doaj.org/article/fe20f16e845c44639e0b8e566373429f
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https://doaj.org/article/fe20f16e845c44639e0b8e566373429f

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