Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
The identification and characterisation of dormant cells is currently difficult. Here the authors report Optical Stem Cell Activity Reporter (OSCAR) to assess RNA polymerase II activity and identify dormant cell populations in intestinal epithelial cells in vivo.
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Main Authors: | Rasmus Freter, Paola Falletta, Omid Omrani, Mahdi Rasa, Katharine Herbert, Francesco Annunziata, Alberto Minetti, Anna Krepelova, Lisa Adam, Sandra Käppel, Tina Rüdiger, Zhao-Qi Wang, Colin R. Goding, Francesco Neri |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/fe29dc36efb94fd6a94dead8d21a2d0f |
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