Modulation and Pharmacology of the Mitochondrial Permeability Transition: A Journey from F-ATP Synthase to ANT
The permeability transition (PT) is an increased permeation of the inner mitochondrial membrane due to the opening of the PT pore (PTP), a Ca<sup>2+</sup>-activated high conductance channel involved in Ca<sup>2+</sup> homeostasis and cell death. Alterations of the PTP have be...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/fe3c2f7d65894b47a6f200869f31c7ba |
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