BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

Amongst the non-small cell lung cancers, to date, lung squamous cell carcinoma remains the most challenging to treat. Here the authors report BCL11A as an important factor which together with SOX2 can drive lung squamous cell carcinoma development and highlight a potential novel therapeutic candidat...

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Main Authors: Kyren A. Lazarus, Fazal Hadi, Elisabetta Zambon, Karsten Bach, Maria-Francesca Santolla, Julie K. Watson, Lucia L. Correia, Madhumita Das, Rosemary Ugur, Sara Pensa, Lukas Becker, Lia S. Campos, Graham Ladds, Pentao Liu, Gerard I. Evan, Frank M. McCaughan, John Le Quesne, Joo-Hyeon Lee, Dinis Calado, Walid T. Khaled
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/fe3fa86c37864591b2b0b229a1e43f44
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https://doaj.org/article/fe3fa86c37864591b2b0b229a1e43f44

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