BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

Amongst the non-small cell lung cancers, to date, lung squamous cell carcinoma remains the most challenging to treat. Here the authors report BCL11A as an important factor which together with SOX2 can drive lung squamous cell carcinoma development and highlight a potential novel therapeutic candidat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kyren A. Lazarus, Fazal Hadi, Elisabetta Zambon, Karsten Bach, Maria-Francesca Santolla, Julie K. Watson, Lucia L. Correia, Madhumita Das, Rosemary Ugur, Sara Pensa, Lukas Becker, Lia S. Campos, Graham Ladds, Pentao Liu, Gerard I. Evan, Frank M. McCaughan, John Le Quesne, Joo-Hyeon Lee, Dinis Calado, Walid T. Khaled
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/fe3fa86c37864591b2b0b229a1e43f44
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Amongst the non-small cell lung cancers, to date, lung squamous cell carcinoma remains the most challenging to treat. Here the authors report BCL11A as an important factor which together with SOX2 can drive lung squamous cell carcinoma development and highlight a potential novel therapeutic candidate for this devastating disease.

Ejemplares similares